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CMC Engineer Intern – Polymer Development M/F/X

Tissium · Paris · publiée le 15 octobre 2026 · ouverte depuis 3 jours · Stage · Salaire non communiqué

Les missions

As part of your end-of-studies internship , you will join Tissium’s CMC (Chemistry, Manufacturing & Controls) team in Paris for 6 months , starting january/february , reporting to a Senior CMC Engineer. The CMC team develops the polymers at the heart of our medical devices . You will contribute to every stage of their development: - deepening our understanding of their structure and physico-chemical properties - designing and optimizing manufacturing processes - running the studies that demonstrate their safety and performance The internship includes a significant share of hands-on lab work , alongside interactions with our external partners and subcontractors.
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Annonce complèteTISSIUM is a mission-driven medical device company founded in 2013 , headquartered in Paris , with a production facility in Roncq (near Lille) and an office in Boston . We are dedicated to creating a new era of body repair by leveraging our biopolymer platform to develop innovative solutions in surgery for a positive impact on patients' lives . TISSIUM's technology is based on research and intellectual property from the laboratories of Professor Robert Langer (MIT) and Professor Jeffrey M. Karp (Brigham and Women's Hospital) , who co-founded the company with Christophe Bancel (CEO) and Maria Pereira (Deputy CEO & Chief Innovation Officer) . We develop polymers for atraumatic tissue repair . Today, they are used for sutureless nerve repair , hernia repair and cardiovascular sealing . Since our inception, we have raised a total of 170 million euros , including 50 million euros in our latest round (April 2023), to finance the commercialization of our first products . YOUR MISSION As part of your end-of-studies internship , you will join Tissium’s CMC (Chemistry, Manufacturing & Controls) team in Paris for 6 months , starting january/february , reporting to a Senior CMC Engineer. The CMC team develops the polymers at the heart of our medical devices . You will contribute to every stage of their development: - deepening our understanding of their structure and physico-chemical properties - designing and optimizing manufacturing processes - running the studies that demonstrate their safety and performance The internship includes a significant share of hands-on lab work , alongside interactions with our external partners and subcontractors. RESPONSIBILITIES In the lab - Perform the experimental work supporting the development of Tissium polymers: chemical reactions, purifications, analytics, performance testing - Help design, perform and follow key testing methods to support the safety and performance of our polymers - Analyze your results and report on them Process development - Support the setup and management of process design and optimization activities, through scale-up and transfer to production, internally or with subcontractors - Help plan and follow up on subcontracted activities: feasibility and optimization work, production planning, batch reviews Verification, validation & documentation - Contribute to the design, planning and follow-up of key verification and validation studies (e.g. stability studies, in vitro degradation studies) - Support the team in writing and reviewing CMC documentation for Tissium products - Work in line with Tissium’s Quality Management System and applicable regulatory requirements YOUR PROFILE Required - Final-year engineering student or equivalent, with a background in chemistry, process development and/or analytics - First hands-on lab experience (internship or project): basic synthesis and purification techniques, use of standard analytical equipment, data analysis and reporting - Professional proficiency in English, written and spoken Nice to have - Knowledge of polymers and/or materials science You are autonomous and well organized, with strong planning and problem-solving skills. You approach technical challenges creatively and are comfortable understanding complex processes involving several partners. You are a team player and eager to learn. WHY JOIN US - A hands-on, end-to-end internship: from the lab bench to production and validation studies, you will see the full development cycle of a medical-grade polymer - Meaningful impact: our polymers are used for sutureless nerve repair, hernia repair and cardiovascular sealing - Real mentoring: day-to-day supervision by a senior engineer of the CMC team - An international environment: 19+ nationalities, with teams in Paris, Roncq and Boston - Internship allowance and benefits: [monthly amount] [+ meal vouchers, transport reimbursement…] PRACTICAL INFORMATION - End-of-studies internship (internship agreement required) - Duration: 6 months, starting in january/february - Location: Paris RECRUITMENT PROCESS - HR video interview (30 min) - Video interview with the manager (1h) - On-site meeting with the team

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